Weird and Rare Skin Disease and Disorder 2
On the first part of my Skin Disorder article, I have post rare cutaneous diseases and here is the second part. We may have it, and we should be aware of these skin diseases.
1) Body Odor
Body odor or B.O., is a foul smell of the body caused by excessive perspiration and multiplied bacteria and grow rapidly on our skin. Sweat is odorless to human, but the condition are known in medical term as; bromhidrosis, apocrine bromhidrosis , bromidrosis , osmidrosis ,ozochrotia, fetid sweat, body smell or malodorous sweating. Body odor of an individual is influenced by diets, lifestyle, gender, genetics, health and medication, and major perspiration (sweating), transpiration or diaphoresis, producing fluid consisting primarily of water as well as kinds of dissolved solids or chlorides excreted by the sweat glands of the skin.
Wearing socks and shoes without enough ventilation for many hours creates unpleasant foot odor, and the main cause is the foot sweat. This create bacteria to produce and grow bad odor substances on our skin, as part of the “human flora”. Hair on the toes, can contribute to intensify the foot odor.
Halitosis or Bad Breath
Halitosis or bad breath, is one of the most unpleasant body odor smelled during exhale or inhale breathing. Common cause for bad breath are abscess of the gum, tooth decay, or the most common location for related halitosis or bad breath is the tongue. The Malodorous compounds and fatty acids are bacterias produced in the tongue that cause foul smells, and putrefaction or decomposition of animal proteins by anaerobic microorganisms. And here are some tools for hygienic oral purposes after brushing our teeth:
Earwax or Cerumin in medical terminology is a yellowish substance secreted in the ear canal of a person or mammals. The earwax protects skin of the ear canal, and helps in clearing and lubricates and protect the ear from fungi, bacteria, water and insects. But we have to clean our ears, because excessive cerumin can press the eardrum and occlude the external auditory canal and impaired hearing. It causes bad odor if the cerumin mixed with vicious modified apocrine sweat glands. According to some research, East Asians and Native Americans are more likely having dry type of earwax because of recessive dominance, and Caucasians and Africans are more likely having wet earwax type.
2) Riga-Fede or Eosinophilic
Riga-fede or Eosinophilic ulcer of the oral mucosa or Eosinophilic ulcer of the tongue, and traumatic eosinophilic granuloma is a condition described as ulcer with an elevated and indurated border.
Venous lake or “Phlebectases”, is an asymptomatic solitary, soft, dark and bluish to violet and compressible, are very common on sun exposed skin surfaces of the vermilion border of the lips, ears or face and this skin lesions affects more on elderly people.
Chondrodermatitis Nodularis Chronica Helius
Chondrodermatitis nodularis chronica helicis, is a small nodular, which is tender, chronic and inflammatory lesion, that occurs on the helix of the ear, most often men are the most affected with this disease.
Michael Jackson, pictured above, claimed to have this weird disease and the treatment he used for his Vertiligo/Vitiligo has caused his complexion to lighten up.
Vertiligo is a chronic cutaneous disorder that causes skin patches pigmentation that occurs when the cell (melanocytes), is responsible for the skin pigmentation or skin to die or unable to function. Vertiligo has unknown causes, but some research they found that it may arise from auto-immune, genetic, neural, viral causes or oxidative stress.
Nevus Depigmentosus or Nevus achromicus, is a skin pigmentation problem but can be differentiate by Vertiligo skin disorder. Age factor is not much involve in the Nevus depigmentosus, but in most cases these skin disorder are noted at birth.
Becker’s nevus or also called “Becker’s melanosis”, “Becker’s pigmentary hamartoma”, “Nevoid melanosis”, and “Pigmented hairy epidermal nevus”, is a cutaneous disorder which is very dominant in males.
Blaschko Lines or Frontal Linear Scleroderma
Frontal Linear Scleroderma, or known as En coup de sabre, Morphea en coup de sabre, is a type of Linear Scleroderma, showing linear band of atrophy and a furrow in the skin, that appears in the ‘frontal’ or ‘fronto parietal scalp. Multiple lesions of En coup de sabre, can exist in a single patient, following some skin lesions and followed by “Blaschko Lines”. Named after the similarity of a sabre wounds or skin lesions.
Striae Distensae (Stretch Mark)
Striae distensae or belly stretchmarks, are depressed bands or lines of thin reddened skin, and after several months, it becomes whiter, smooth, shiny and depressed that occurs when there changes in weight or muscle mass and skin tensions. Striae Gravidarum are skin disorders of lesion of capillaries, resulting in small marks on the belly or abdomen, during and following pregnancy.
Localized Merc Morphea
Localized morphea, is a form of “Scleroderma” that appears more on women than in men. It usually appears in childhood until adulthood, and present oftentimes, as “macules” or plaques a few cm in diameter, but may also appear like bands or in ‘guttate lesions’ or ‘nodules’.
Mongolian spot or “Mongolian Blue-spot”, is a congenital melanocytosis skin disorder and Dermal melanocytosis, is non-cancerous, flat congenital birthmark with irregular shapes and way-borders, named after Erwin Balz, a Mongolian; and commonly appears among East Asians, Native Americans, Polynesians, and East Africans; but disappear at three or five years after birth or stays until the puberty age.
4) Leprosy or Hansen’s Diseaseb> (HD)
Another weird disease, Leprosy or Hansen’s disease (HD), is a chronic cutaneuos disease caused by Mycobacterium Leprae Bacteria and Mycobacterium Lepromatosis. Leprosy or Hansen’s disease is primarily a ‘Granulomatous’ disease of the peripheral nerves and mucosa of the upper respiratory tract, and the skin lesions are the primary visible sign in the skin layer. Leprosy cna grow progressively if untreated and will cause permanent damages in the skin tissue, especially nerves, limbs, eyes, ear and nose. Leprosy as we believed that it will cause tissue loss, ears, nose, fingers or toes, or body parts to fall off, but the truth is; Leprosy affected areas becomes numb, resulting to severe infection and causes fingers, toes or tissue to shortened and be deformed as the cartilage is absorb by the body.
5) X-Linked Ichthyosis (XLI)
X-linked ichtyosis (XLI) also called “Steroid Sulfatase deficiency”, and “X-linked Recessive Ichtyosis”, is a hereditary deficiency of the steroid sulfatase(STS) enzyme that affects most on men skin. The XLI is a dry-scaly skin and is due to mutations or deletions in the STS genes, and this disease has no cure.
Blau syndrome is described as familial granulomatous arthritis, Iritis, and skin granulomas, consisting adominance in genetics or autosomal dominantly inherited disease that overlaps both “Sarcoidosis and grnuloma annulare”. The rare skin disorder, Blau syndrome, have dominant disorder described by granulomatous polyarthritis, panuveitis, cranial neuropathies and exanthema.
6) Neuro Fibromatosis
Neurofibromatosis Type 1, was formerly called as von Recklinghausen disease, after the researcher Friedrich Daniel von Recklinghausen first documented this human genetic skin disease. This skin disorder is commonly inherited by single gene. NF1 is different from Proteus syndrome which may affected the “Elephant man”. NF1 is a skin tumor caused by malfunction of a gene chromosome 17 and is responsible for controlling cell division, but the tumors are non-cancerous lumps.
7) Mycosis Fungoides (Alibert-Bazin Syndrome)
Mycosis Fungoides or otherwise called “Alibert-Bazin syndrome” or ‘granuloma fungoides’, is the most common cutaneous disease, “T-cell carcinoma”. Generally affecting the skin but can progress deeper into the skin and tissue. Although it is not considered fungal infection, but it is a type of “Non-Hodgkin’s Lymphoma”, and the severe skin infection is described as “mushroom-ike” appearance.
Pellagra skin disorder are characterized by “The Four Ds”, dermatitis, diarrhrea, dementia and death. The symptoms are having agressions or behavior, alopecia or loss of hair, dermatitis, sensitivity to sunlight, edema, inflammation of the tongue (Glossitis), red-skin lesions, weakness and insomnia, mentally confused, paralysis of extremities, peripheral neuritis, dilated cardiomyopathy (DCM),weakened and enlargement of the heart or ataxia.
Herpes Simplex, a viral skin disease caused by both Herpes Simplex virus type 1 (HSV-1) and Type 2 (HSV-2). The herpes simplex virus, are divided into variant distinct cutaneous disorder based on the infection type. The “Oral herpes”, has the most visible symptoms and known as, “cold sores” or “fever blisters“, that infects mostly the face and mouth. The “Genital Herpes”, are simply called ‘herpes’, and the most second common type of herpes virus, and oftentimes associated with impaired immune function as HIV/ AIDS, immunosuppression in solid organ transplants.
Pyogenic granuloma or known as “Eruptive Hemangioma”, “Granulation Tissue-type hemangioma”, “Granuloma gravidanum”, “Lobular Capillary hemangioma”, “Pregnancy tumor” is formerly known as oral disease, appearing as overgrowth of tissue caused by irritation, physical trauma or hormonal factors. Most often affecting the nasal septum and skin( dividing the two nostrils, left and right airways).
Hemangioma of infancy are non-cancerous(benign) growing or swelling tumors, of ‘endothelial cells’, the cells that group the blood vessels and appear usually during the first week of life and resolves at the age of ten. Hemangioma are common tumor for the infants.
10) Discoid Lupus Erythematosis (DLE)
Discoid Lupus Erythematosus (DLE) is a chronic skin sores disorder, with inflammation and scarring, commonly grows on the face, ears, scalp and other body areas. Reddish, patches inflammation with scaly and crusty appearance of this DLE, appear in light color with a rim darker areas than the normal skin.
11) Chronic Erythema Nodosium
Chronic erythema nodosum also called, “Erythema Nodosum Migrans”, “Subacute Migratory Panniculitis of Vilanova and Pinol”, and “Subacute nodular migratory Panniculitis”, is a form of Septal panniculitis which is not common than acute Erythema Nodosum.
12) Angio Keratoma
Angiokeratoma is a red to bluish color small marks and a benign cutaneous lesions of the capillaries, and described as heperkeratosis. The “Angiokeratoma corporis diffusum”, refer’s to Fabry’s Disease, but usually it is considered as distinct condition of the skin, that includes ‘Telangiectasia, acanthosis, and hyperkeratosis”.
Telangiectasia are small dilated blood vessels near the skin surface or mucous membranes, as seen in picture. Acanthosis, is an epidermal diffused hyperplasia and implies increased the thickness of the “Stratum spinosum. The hyperkeratosis is the thickening of the stratum corneum, and oftentimes related with keratin abnormality, that caused by Vitamin A deficiency or exposure to arsenic chemicals.
13) Fordyce’s Spots
Fordyce’s Spots are small, painless, pale and raised red or white spots or bumps 1 to 3 mm in diameter, that appear and grow on the penis’ shaft or labia and even in the inner surface (retromar mucosa) and vermilion border of the lips of the face. These disease are common in men and women of all ages.
Tyson’s glands or head of the penis, should not be confused with Hirsuties Papillaris Genetalis or Hirusities Coronae Glandis or penis glands.
Dyshidrosis or also called “Acute vesiculobulous hand eczema”, “Cheirpompholyx”, “Dyshidrotic eczema”, “Pompholyx” and “Podopompholyx”, is a skin disorder described as small blisters on the hands or feet. Dyshidrosis is a recurrent dermatosis, and acute and chronic skin disorder of the fingers, palms and soles, with deep-seated pruritic (itchy), clear vesicles; (dermatology), later, scaling fissures and lichenification appear. Some people believed that “bad sweating” or dyshidrotic causes this skin diseases, nut it was not medically proven, and there ares some factors that trigger the outbreaks of dyshidrosis like emotional stress, allergies, and climate change that aggravate the condition.
Frostbite or in medical terminology, “Conelatio i”, is a medical condition, where skin damaged and other tissues when exposed to extreme coldness. Frostbiet occurs when the body parts from the heart to large exposed skin areas are affected and the initial stages of frostbite is called “frostnip“.
Wintertenen or Chilblains
Wintertenen or Chilblains, also called “pernio and perniosis”, is the medical skin condition, and oftentimes confudes as ‘frostbites’ and ‘trench foot’. Chilblains are known as acral ulcers, when predisposed individual’s skin disorder to cold and humidity.
Trench Foot is a medical condition caused by prolonged exposure of the feet on damp, dirty and cold condition and one of many immersion foot syndrome. Trench word, named after trench warfare related with World War1.
16) Pyoderma Gangrenosum
Pyoderma Gangrenosum, is a skin disease that causes the skin tissues to become “necretic” (premature death of cell), that causes deep ulcers or wounds of the skin that commonly affect the legs. Pyoderma gangrenosum, do not lead to death of the patient, but can cause severe pains and scarring.
Necrotic leg wound caused by Brown Recluse Spider bites. It is also called “violin spider”, commonly found in Midwest south to Gulf of Mexico, Nebraska, Iowa, Illinois and Indiana.
Severe tissue Necrosis of an eleven year old boy after he was bitten by bothrops asper snake, amputation above the knee is the only treatment for such severe necrosis wounds.
17) Erythropoeietic Protoporphyria (EPP)
Erythropoietic Protopophyria or EPP, a kind of painful form of skin disease, arising from “enzyme ferrochelatase” deficiency, that leads to abnormality of high level s of protoporphyrin tissues, and patients with this skin condition have high risk of developing gallstone in the gallbladder. Some cases of EPP, can accumulate toxic levels in the liver and causes liver disease.
18) Xanthoma Tendinosum
Xanthoma Tendinosum, also called Xanthelasma, is the yellowish collection of cholesterol, underneath the skin, or sometimes found mostly around the eyelids.
Calciphylaxis syndrome of vascular process in which calcium salts build up in soft tissues, that cause to harden or also called “calcification”, thrombosis and skin necrosis. Patients with stage 5 chronic kidney disease, are the most affected with this kind of skin disorder. And it also result to chronic non-healing wounds and sometimes causes death. Calciphylaxis are rare skin diseases, but can be fatal. Patients with milk alkali syndrome , sarcoidosis, primary hyperparathyroidism, and hypervitaminosis D, are prone to Calciphylaxis disease.
20) Henoch-Schonlein Purpura
Henoch-Schonlein Purpura (HSP), is a kind of skin disorder and other body organs, and usually the children are affected with this skin disease, causing small hemorrhages (palpable purpura), with abdominal pains and pains of the joints as symptoms. If the kidney is affected, there maybe loss of small quantity of protein and blood in the urine but sometimes it is not noticeable. Pharyngitis infection follows usually patients with HSP.
Keratosis Pilaris (KP), also called “follicular keratosis”, and commonly known ‘chicken skin’, is genetic, autosomal dominant, skin condition with rough bumps appearance, and usually appears at the back and outer sides of upper and lower arms, but sometimes appears on the thighs, hands and tops of the legs, flanks, buttocks or other areas of the body skin, except the palms and sole of feet, which is the glabrous skin (non-hairy). When KP appear on the face it is sometimes mistaken for acne. Depression and anxiety are said to be one causes of ‘keratosis pilaris’.
Goose bumps also called ‘chicken skin’, develop when we feel frightened, weird eerie feelings, coldness, scared with something we feel, or any strong emotions caused by fear, awe, admiration, or even sexual arousal.
21) Buruli Ulcer
Buruli ulcer or also known as Bairnsdale ulcer, or “searl ulcer”, is an infectious skin disease, caused by “Mycobacterium ulcerans”, and this genus, includes leprosy and tuberculosis. Most infections affects the limbs, and exposed body areas, with painless nodules and non-pyogenic, necrotic skin lesions that affects the skin and even the adjacent bones.
22) Raynaud’s Phenomenon
Raynaud’s Phenomenon is a “vasospatic” disorder that causes toes and finger’s discoloration and sometimes can be visible in some areas of the body and sometimes causes nail brittleness. In some studies, they believe that the vasoplasms decreased blood supply to their respective body organs. Cold areas and emotional stress are believed to trigger the phenomenon. In some severe causes, the phenomenon can progress to necrosis or gangrene of the fingertips.
23) Lichen Planus
Lichen Planus is a chronic mucocutaneous skin disease, affecting skin, tongue, mucos membrane of the mouth (oral mucusa). Lichen planus is characterized by papules, skin lesions or rashes and chronic inflammatory skin disease of unknown etiology with 1 to 2mm, uniform and discrete, shiny, flat-topped, pale-flesh, reddish-brown papules and some are hypopigmented by blacks. Lichen Sclerosus (LS), or also called Lichen Sclerosus ot Atrophicus, a rare and not common skin disease, of unknown causeresulting to ‘white patches’ on the skin, causing scarring on or around the genital organ skin.
Phimosis, a skin condition on a male’s foreskin of the penis, that did not fully retracted from the penis’ head. It also refers to “clitoral phimosis” in women case, where the clitoris hood cannot be retracted, that limits the exposure of the ‘glans clitoridis’.
Keloid or Keloidal Scar, is a kind of scar on the skin, resulting from any kind of wounds, or surgical wounds and overgrowth of granulation tissue (collagen type 3), at the healed areas of the skin caused by injury or surgery, which slowly replaced by collagen type 1, and depending on the scar’s maturity, composing of either early stage of type 3 collagen or late type 1 of collagen.
Kwarshiorkor Skin Disease
This is another weird disease which is often seen in countries that have high poverty rates. Kwarshiorkor, is an acute childhood protein energy malnutrition, leading to edema, anorexia, irritability, dermatosis ulcers, and enlargement of the liver with fatty infiltrates.